Niacinamide, Peptides, Hyaluronic Acid, and Retinol — Do They Work, How Do They Work, and When Should They Be Used?
- Miriam Ribeiro
- Dec 27, 2025
- 3 min read
A YARÁ Spa & Skin Care Insight
Many skincare products highlight ingredients like Niacinamide (Vitamin B3), Peptides, Hyaluronic Acid, and Retinol. Each plays a different role, and understanding how they work can help you choose products in a way that feels intentional and supportive for your skin.
At YARÁ, we focus on gentle, knowledge-driven skincare — avoiding extremes and helping the skin remain comfortable, resilient, and balanced.
Hyaluronic Acid — Hydration Support
What it is
A naturally occurring water-binding molecule that helps the skin retain moisture.
How it works
Acts like a surface hydration magnet, increasing softness and comfort.
Best for
Dry, tight, or dehydrated-feeling skin
Winter or dry climates
Daily comfort support
Good to know
Works best when followed with a moisturizer to seal hydration in.
Hyaluronic Acid supports hydration and comfort, not resurfacing or correction.
Niacinamide (Vitamin B3) — Balance & Barrier Support
What it is
A versatile vitamin-based ingredient often used to support skin balance and resilience.
How it works
Helps improve barrier comfort
Supports a more even-looking tone
Can reduce the appearance of excess oil or visible pores
Best for
Unbalanced or reactive-feeling skin
Combination or oily-prone skin
Long-term, gentle maintenance
Good to know
Moderate strengths are often more comfortable than very high percentages.
Niacinamide is a steady, supportive ingredient rather than a fast-acting one.
Peptides — Conditioning & Supportive Care
What they are
Short chains of amino acids, used to condition and support the feel of the skin.
How they work
Complement moisturizers
Help the skin feel smoother and more supported
Provide a soft, nurturing effect over time
Best for
Mature or tired-looking skin
Dry or delicate-feeling skin
Nighttime or nourishment-focused routines
Good to know
Peptides offer gentle enhancement, not dramatic transformation.
Peptides are most helpful in comfort-focused, barrier-respecting routines.
Retinol — Renewal & Skin-Activity Support (Use Thoughtfully)
What it is
Retinol is a vitamin A derivative commonly used in “renewal” or anti-aging skincare.
How it works
Encourages cell-turnover activity at the surface layers
Can improve the appearance of texture, fine lines, and uneven tone over time
Often considered one of the more active ingredients in skincare
Best for
Skin that is comfortable with active ingredients
Evening routines
Gradual, long-term improvement goals
Use with care
Can cause dryness or sensitivity if overused
Works best when paired with moisturizers and barrier-supporting ingredients
Not ideal for already fragile, irritated, or barrier-stressed skin
At YARÁ, we view Retinol as a tool to be used thoughtfully, not aggressively.

Which Ingredient Is Right for My Skin?
Think in terms of what your skin needs right now:
Skin Need | Ingredient Match |
Feels tight, dry, or dehydrated | Hyaluronic Acid |
Feels unbalanced, oily-prone, or reactive | Niacinamide |
Feels fragile, tired, or in need of comfort | Peptides |
Seeking gentle renewal or texture refinement (and tolerates activity) | Retinol |
Many routines may combine more than one of these ingredients — especially when the focus is gentle, supportive care.
A Philosophy of Care Over Aggression
At YARÁ Spa & Skin Care, we believe effective skincare should feel:
calming
consistent
respectful of the skin’s natural rhythm
Rather than chasing harsh or rapid change, we support the skin in building strength, comfort, and resilience over time.
If you’re unsure which ingredients align with your skin’s needs, we offer personalized consultations to help guide your choices in a way that feels safe, supportive, and intentional.
Book a consultation or message us — we’re here to help you care for your skin with understanding and purpose.




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